Mary Ann Coffey, a practicing Clinical Pharmacist for over 15 years, has become passionate about integrative and functional medicine that further enhances the body’s natural ability to heal. She practices patient-centered, individualized, and focused care.

She develops easily understandable, clinically relevant programs for her clients,   guiding their path to long-term improvement. Her expertise in pharmaceutical and nutraceutical products is an invaluable source of information, and can quickly improve the lives of those around her.

Mary Ann offers the following:
 
     *  MTM (Medication Therapeutic Management)

     *  Metabolic Code Health and Vitality Assessment Report
           ~  Utilizing personal questionnaire responses
           ~  Biometrics
           ~  Lab Tests Result (Full Functional Lab assessment)

     *  BHRT (Bioidentical Hormone Replacement Therapy)

Mary Ann believes in living a balanced life. Her interests vary from Tae Kwon Do to Ball Room Dancing. She loves the outdoors, running, bike riding, and hiking.

The United States utilizes 5X more Ritalin than the entire world combined. There are an enormous amount of nutrients that are depleted by Female hormones medications including Folic Acid, B vitamins, Tyrosine, Magnesium,  Zinc. Co-Q10

It’s not uncommon for people taking multiple medications depleting the same nutrient. An example would be Folic Acid and Co-Q10 depleted by cholesterol-lowering agents, female hormone, anti-hypertensives, and antidepressants. 

Why? Drugs can inhibit the nutrient absorption synthesis, transport storage, metabolism and excretion of nutrients.  Health problems are very multi-factorial and complex. Just about everyone is under a severe amount of stress and just about 50% of our meals are consumed by the fast food industry. The nutritional content of your locally bought food has declined significantly over the years and level of pollution are greater than any time in reported history.

As a clinical nutritionist, I can examine the medications that you are on and make recommendations of what nutrients may have been depleted over time and manifesting as a side effect of the medication.

DIND: Drug-Induced Nutrient Depletions

Since there is no baseline nutritional analysis in clinical trials of new medications, interactions of medication and nutritional status go undiscovered until after the drug has already been released and is in use. known existing drug-induced nutrient depletions are not taught in medical school curriculums, only a limited number of nutrition-related side effects of drugs are ever likely to be observed by a medical practitioner. 

In the mainstream literature of pharmacology, drug-nutrient interactions are typically placed in three categories:

  • drug-alcohol interactions,
  • drug-food incompatibility,
  • drugs affecting nutritional status. 

Interference of diet with drugs is more likely to be noticed by physicians than interference of drugs with nutrient status. When a medication is expected to be effective in a specified dosage for a specified condition and it is not, the cause is quickly investigated. If nutrients were investigated on the same standard we would not have an epidemic nutrient deficiency.

For instance, when a patient placed on warfarin (Coumadin) for a few weeks does not test for a longer prothrombin (PT) time, either the doctor or the pharmacist is likely to inquire immediately whether the patient is eating large quantities of green leafy vegetables rich in vitamin K. The effects of nutrition on medication result in symptoms quickly and are corrected quickly. 

The effects of medication on nutrient status, however, can take place more slowly. For example, the liver may require additional nutrients to clear a drug, and this extra demand for the nutrient depletes them over time. If there are no other unusual demands for the nutrients, they may not be depleted while the patient is under a doctor's care.  Only when a new stressor is encountered does nutrient depletion become obvious. The straw that breaks the camel’s back. Likewise, if the nutrient status of a person is compromised but not deficient before drug therapy is initiated, it may not produce obvious symptoms until after the disease the drug is used to treat has run its course or the patient is on a maintenance dosage. 

  1. Medications may cause electrolyte imbalances, leading to muscle spasm, cramping, palpitations, headaches and muscle weakness. 
  2. Mineral and vitamin D deficiencies can lead to osteopenia and osteoporosis. 
  3. Several categories of drugs deplete CoQ10, which can affect the genetic expression of muscle fibers, neural integrity, and energy production. 
  4. Nutrient depletion issues can pose as problems in coordination and balance.

Drug-Induced Nutrient Depletion (DIND) can alter synthesis, storage, transport, metabolism and excretion of essential vitamins, minerals, fatty acids and amino acids as well as vitamin cofactors. 

  1. The amount of each nutrient depleted by drug therapy is dependent on complex factors, such as gender, genetics, absorption, intake and individual lifestyle choices. 
  2. Functional deficiencies may not be observed as symptoms, conditions or disease progression for a period of months or years after initiation of drug therapies. 
  3. Chronic prescription or over the counter drug use may result in single nutrient or complex vitamin, mineral, and cofactor deficiencies.

Birth Control Pill: Vitamin B12 which causes anemia fatigue, tiredness, and weakness. Vitamin B12 is common cause of depression especially in elderly people.

In 1998 oral contraceptives constituted the 14th largest category of prescription drug in the United States accounting for more that $1.6 Billion in sales. 

How Can Mary Ann Help You?

  • Pharamcogenomics
  • Metabolic Code Assessment  which includes a functional lab assessment.
  • DIND (Drug Induced Nutrient Deficiencies)
  • Drug-Drug Interactions Drug- Herb Interaction Review 

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Mary Ann Coffey